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| Antigenic Specificity | TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) |
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| Clone | 3B5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. |
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| Immunogen | Purified recombinant fragment of human TAB2 expressed in E. coli. |
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| Other Names | CHTD2|MAP3K7IP2|1110030N06Rik|A530078N03Rik|Map3k7ip2|mKIAA0733|map3k7ip2|zgc:77446 |
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| Gene, Accession # | Gene ID: 23118 |
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| Catalog # | ABIN969430 |
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| Price | |
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| Order / More Info | TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 17047224, 16384851, 20493459 |
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