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Product Name | Linoleoyl Glycine |
Description | Purity >98%. Arachidonyl glycine, the conjugate of arachidonic acid and glycine produced in mammalian brain, skin, and spinal cord, is a structural analog of anandamide (AEA) that is reported to have analgesic activities in whole animal experiments. It has poor affinity for the central cannabinoid (CB1 ) receptor, high-affinity for the G protein-coupled receptor GPR-18, and is metabolically regulated by fatty acid amide hydrolase (FAAH) activity. LinGly is an endogenous homolog of linoleoyl ethanolamide, an arachidonyl glycine. It inhibits the hydrolysis of AEA in FAAH-containing N18TG2 cell membranes with an IC50 value of ~25 µM, which is less potent than that of arachidonyl glycine (IC50 = 7 µM). The biological significance of LinGly has not yet been determined. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-9Z,12Z-1-oxo-octadecadien-1-yl-glycine, Glycine Linoleamide, LinGly, N-Linoleoyl Glycine |
Gene, Accession, CAS # | CAS: 2764-03-6 |
Catalog # | LS-H8488 |
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Order / More Info | Linoleoyl Glycine from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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