| 产品详情 |
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| Product Name | GNF-7 |
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| Description | Purity >98% by HPLC. GNF-7 is a multi-targeted kinase inhibitor that inhibits activated CDC42 kinase 1 (ACK1) and germinal center kinase (GCK) inducing cell cycle arrest and apoptosis in leukemia cells harboring NRAS mutations. It also displays significant in vivo efficacy against T315l-Bcr-Abl without notable toxicity in a bioluminescent xenograft mouse model using transformed T315l-Bcr-Abl-Ba/F3 cell line that has a stable luciferase expression. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide |
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| Gene, Accession, CAS # | CAS: 839706-07-9 |
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| Catalog # | LS-H3846 |
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| Order / More Info | GNF-7 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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