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Product Name | GBA, 40-536aa, Human, His tag, Baculovirus |
Description | MW: 56.4kDa (503aa) 50-70kDa (SDS-PAGE under reducing conditions). Purity >80% by SDS-PAGE. GBA, also known as glucosylceramidase isoform 1, is a lysosomal enzyme that presumably requires a signal peptide for transport across the membrane of the rough endoplasmic reticulum and glycosylation for transport into lysosomes. Gaucher disease is due to a deficiency in the activity of the enzyme glucocerebrosidase. Recombinant human GBA, fused to His-tag at C-terminus, was expressed in insect cell and p |
Size | 0.05 mg, 0.25 mg |
Concentration | 0.5 mg/ml (determined by Absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | [Glucosylceramidase isoform 1; GBA1; GCB; GLUC] |
Gene, Accession, CAS # | GBA, Gene ID: 2629, Accession: NP_000148 |
Catalog # | MBS206272 |
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Order / More Info | GBA, 40-536aa, Human, His tag, Baculovirus from MYBIOSOURCE INC. |
Product Specific References | Sorge JA., et al. (1987) Am J Hum Genet. 41:1016-1024.; Salvioli R., et al. (2000) FEBS Lett. 472:17-21. |
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