| 产品详情 |
| Edit |   |
|---|
| Product Name | Oxolinic Acid |
|---|
| Description | Purity >98%. Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Oxolinic acid is a quinolone antibiotic that inhibits bacterial DNA gyrase, but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 µg/ml. Oxolinic acid also blocks neuronal uptake of dopamine in mammals (IC50 = 4.3 µM), leading to an increase in locomotor activity. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid, NSC 110364, Urinox |
|---|
| Gene, Accession, CAS # | CAS: 14698-29-4 |
|---|
| Catalog # | LS-H9225 |
|---|
| Price | |
|---|
| Order / More Info | Oxolinic Acid from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|