产品名称 DMRT1 Antibody from LIFESPAN BIOSCIENCES INC.
产品货号 LS-C502220
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 LIFESPAN BIOSCIENCES INC.
产品概述
产品详情
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Antigenic SpecificityDMRT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatbiotin conjugate
Sizen/a
Concentrationn/a
ApplicationsELISA
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DescriptionDMRT1 Antibody (Biotin) LS-C502220. Specificity: Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).
ImmunogenRecombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA)
Other NamesDMRT1, DMT1
Gene, Accession #DMRT1, Gene ID: 1761
Catalog #LS-C502220
Price
Order / More InfoDMRT1 Antibody from LIFESPAN BIOSCIENCES INC.
Product Specific Referencesn/a
产品资料