| 产品详情 |
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| Product Name | Paxilline |
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| Description | Purity >95% by HPLC. Tremorgenic. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium (BKCa) channels. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor (InsP(3)). Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor. Liver X receptor (LXRalpha and LXRbeta; NR1H3 and NR1H2) agonist in biochemical and in vitro cell-based assays. Anticonvulsant. Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis. Shown to protect neuronal cells against glutamate-induced cell death. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BRN 5317894, NSC 658707 |
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| Gene, Accession, CAS # | CAS: 57186-25-1 |
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| Catalog # | LS-H453 |
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| Order / More Info | Paxilline from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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