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| Product Name | Astemizole |
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| Description | Purity >98%. Astemizole is a non-sedating antihistamine that antagonizes the histamine H1 receptor with a Ki value of 4.4 nM. It is considerably less potent at muscarinic acetylcholine receptors (Ki = 2.4 µM). Astemizole is also a potent blocker of ether-a-go-go-related gene (ERG) potassium channels (IC50 = ~1 nM) that has been used to study long QT syndrome type 2. Furthermore, because it can target oncogenic ERG1 and ERG potassium channels, astemizole has been explored as a potential antineoplastic agent for decreasing proliferation of various cancer cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine, NSC 329963 |
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| Gene, Accession, CAS # | CAS: 68844-77-9 |
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| Catalog # | LS-H6642 |
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| Order / More Info | Astemizole from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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