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| Product Name | WM3540 Purified RNA |
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| Description | Total RNA was prepared from cell line WM3540. WM3540 is a human metastatic melanoma cell line that displays a pigmented, mesenchymal morphology. This cell line was established from a lymph node metastases of a patient. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses D97H mutation in CDK4 gene and is wild type for N-RAS and c-KIT. WM3540 cells produce xenograft tumors when injected into immunocompromised mice. |
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| Size | 10 µg |
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| Concentration | 200 ng / µl |
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| Applications | Purified RNA is suitable for a number of molecular biology applications including but not limited to next generation sequencing and expression library construction, PCR, real-time PCR, microarray analysis, and transfection experiements. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | WM3540-04-0500 |
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| Order / More Info | WM3540 Purified RNA from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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