| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | ROC2, C-terminus |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | delipidated & defibrinated |
|---|
| Size | 100 µL |
|---|
| Concentration | 85 mg/mL |
|---|
| Applications | ELISA, Immunohistochemistry, Western Blot. This antibody reacts with human ROC2 by western blot and immunoprecipitation. The antibody immunoprecipitates in vitro translated protein and protein from overexpressing cell lysates (using HeLa and NIH-3T3, and others). Coimmunoprecipitation of related proteins does occur. A 12.6 kDa band corresponding to human ROC2 is detected. Most cell lines expressing ROC2 can be used as a positive control. Researchers should determine optimal titers for other applications. |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human, mouse, C.elgans and zebra fish ROC2. Cross reactivity may also occur with ROC2 from other sources. Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and APC11. |
|---|
| Immunogen | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 102-113 of Human ROC2 (C-terminal) coupled to KLH. |
|---|
| Other Names | rabbit anti-ROC2 antibody, GTP binding protein Roc2 antibody, Ras like protein expressed in neurons antibody, Ras like without CAAX 2 antibody, Ras like without CAAX protein 2 antibody, RIBA antibody, Ric (Drosophila) like antibody, Ric like antibody, RIN antibody |
|---|
| Gene, Accession # | RNF7, Gene ID: 9616, NCBI: 37538003, UniProt: Q9UBF6 |
|---|
| Catalog # | 100-401-A14 |
|---|
| Price | |
|---|
| Order / More Info | ROC2, C-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
|---|
| Product Specific References | Kamura,T., Koepp,D.M., Conrad,M.N., Skowyra,D., Moreland,R.J., Iliopoulos,O., Lane,W.S., Kaelin,W.G. Jr., Elledge,S.J., Conaway,R.C., Harper,J.W. and Conaway,J.W. (1999) Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284 (5414), 657-661.Ohta,T., Michel,J.J., Schottelius,A.J. and Xiong,Y. (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol. Cell 3 (4), 535-541. Seol JH,Feldman RM,Zachariae W,Shevchenko A,Correll CC,Lyapina S,Chi Y,Galova M,Claypool J,Sandmeyer S,Nasmyth K,Deshaies RJ,Shevchenko A,Deshaies RJ, (1999) Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev. 13:12, 1614-1626. |
|---|
| 产品资料 |
|
|