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Antigenic Specificity | TNFSF11 |
Clone | 4H242 |
Host Species | Recombinant Mouse |
Reactive Species | mouse |
Isotype | IgG1 |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse Anti-TNFSF11 Recombinant Antibody (4H242). This product is a Mouse antibody that recognizes TNFSF11. The antibody 4H242 can be used for immunoassay techniques such as: WB. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tum |
Immunogen | Bacterially expressed GST-fusion protein containing aa. 1-317 of mouse TRANCE |
Other Names | TNF Superfamily Member 11; Tumor Necrosis Factor (Ligand) Superfamily, Member 11; TNF-Related Activation-Induced Cytokine; Osteoclast Differentiation Factor; Osteoprotegerin Ligand; TRANCE; RANKL; OPGL; ODF; Receptor Activator Of Nuclear Factor Kappa B Ligand; Receptor Activator Of Nuclear Factor Kappa-B Ligand; |
Gene, Accession # | Gene ID: 21943, UniProt: O35235 |
Catalog # | CBMAB-R4053-CN |
Price | |
Order / More Info | TNFSF11 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |