Edit |   |
Antigenic Specificity | TNFSF11 |
Clone | DN254 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human Anti-TNFSF11 Recombinant Antibody (DN254). This product is a recombinant human antibody that recognizes TNFSF11. The antibody DN254 can be used for immunoassay techniques such as: FC. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC ki |
Immunogen | n/a |
Other Names | TNF Superfamily Member 11; Tumor Necrosis Factor (Ligand) Superfamily, Member 11; TNF-Related Activation-Induced Cytokine; Osteoclast Differentiation Factor; Osteoprotegerin Ligand; TRANCE; RANKL; OPGL; ODF; Receptor Activator Of Nuclear Factor, κ B Ligand; Receptor Activator Of Nuclear Factor, κ-B Ligand; |
Gene, Accession # | Gene ID: 8600, UniProt: O14788 |
Catalog # | CBMAB-C3655-CQ |
Price | |
Order / More Info | TNFSF11 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |