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Product Name | CFTR Inhibitor-172 |
Description | MW: 409.4. Purity ≥98% by HPLC. Background: A potent, reversible, selective, CFTR chloride channel blocker. Inhibits CFTR short-circuit current in < 2 minutes in a voltage-independent manner (Ki = ~ 300 nM). At concentrations fully inhibiting CFTR, CFTR(inh)-172 does not block increase of cellular cAMP or inhibit non-CFTR Cl(-) channels, multidrug resistance protein-1 (MDR-1), ATP-sensitive K(?) channels, or a series of other transporters. |
Size | 1 mg, 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [4-[[4-Oxo-2-thioxo-3-[3-trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]benzoic acid; CFTR(inh)-172] |
Gene, Accession, CAS # | CAS: 307510-92-5 |
Catalog # | MBS843200 |
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Order / More Info | CFTR Inhibitor-172 from MYBIOSOURCE INC. |
Product Specific References | n/a |
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