产品详情 |
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Product Name | Insulin (INS-B) (AA 9-23) peptide |
Description | This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic beta cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | igf2-A|ins|ins1|xins |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN987527 |
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Order / More Info | Insulin (INS-B) (AA 9-23) peptide from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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