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| Product Name | Arf6 Activation Assay |
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| Description | Background: Small GTP-binding proteins (or GTPases) are a family of proteins that serve as molecular regulators in signaling transduction pathways. Arf, a 20 kDa protein of the Ras superfamily, regulates a variety of biological response pathways that include vesicle trafficking, organelle structure, and endocytosis. Like other small GTPases, Arf regulates molecular events by cycling between an inactive GDP-bound form and an active GTP-bound form. In their active (GTP-bound) state, Arf1 and Arf6 |
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| Size | 5 assays, 20 assays, |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168167 |
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| Order / More Info | Arf6 Activation Assay from MYBIOSOURCE INC. |
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| Product Specific References | 1. Moss J., Vaughan M. (1998) J. Biol. Chem. 273:21431-214344.2. Moss J., Vaughan M. (1995) J. Biol. Chem. 270:12327-12330.3. Kahn R. A., Gilman A. G. (1986) J. Biol. Chem. 261:7906-7911.4. Rothman J. E. (1994) Nature 372:55-63.5. Donaldson J. G., Jackson C. L. (2000) Curr. Opin. Cell Biol. 12:475-482.6. Donaldson J. G., Klausner R. D. (1994) Curr. Opin. Cell Biol. 6:527-532.7. Dell'Angelica EC, Puertollano R, Mullins C, et al. (2000) J Cell Biol. 149: 81-94.8. Takatsu H, Yoshino K, Toda K, Nakayama K. (2002) Biochem J. 365: 369-378.Grossmann, A. Et al. (2013). The Small GTPase ARF6 Stimulates beta-Catenin Transcriptional Activity During WNT5A-Mediated Melanoma Invasion and Metastasis. Sci. Signal. 6:ra14. |
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