| 产品详情 |
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| Antigenic Specificity | Thimet Oligopeptidase/THOP1 |
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| Clone | 4D6 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat, primate, rabbit |
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| Isotype | IgG2b |
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| Format | Protein A purified |
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| Size | 0.1 ml |
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| Concentration | 1.54 mg/ml |
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| Applications | Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin. This Thimet Oligopeptidase (4D6) antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin-embedded sections and Western blot, where a band is seen at 80 kDa. For IHC-P, this antibody has been tested in human, monkey, and rat brain and testis. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The Thimet Oligopeptidase/THOP1 Antibody (4D6) from Novus Biologicals is a mouse monoclonal antibody to Thimet Oligopeptidase/THOP1. This antibody reacts with human, mouse, rat, primate, rabbit. The Thimet Oligopeptidase/THOP1 Antibody (4D6) has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin. Thimet oligopeptidase, a widely distributed enzyme in most species, plays a role in the metabolism of short neuropeptides (under 20 a.a. residues long). Thimet Oligopeptidase has an influential role in cytoplasmic peptide degradation. Other functions of Thimet Oligopeptidase include the degradation of amyloid precursor protein and the production of amyloidogenic fragments. |
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| Immunogen | A synthetic peptide corresponding to residues 56-72 of human Thimet Oligopeptidase. [UniProt# P52888] |
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| Other Names | EC 3.4.24, EC 3.4.24.15, Endopeptidase 24.15, EP24.15, MEPD_HUMAN, MP78, thimet oligopeptidase, thimet oligopeptidase 1, TOP |
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| Gene, Accession # | THOP1, Gene ID: 7064, Accession: P52888, SwissProt: P52888 |
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| Catalog # | NB400-146 |
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| Price | |
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| Order / More Info | Thimet Oligopeptidase/THOP1 Antibody from NOVUS BIOLOGICALS, LLC |
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| Product Specific References | PubMed: 18582092, 8780030 |
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