| 产品详情 |
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| Product Name | GSK621 |
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| Description | Purity >98%. GSK621 is an activator of AMP-activated protein kinase (AMPK). It has been shown to increase phosphorylation at AMPKAlpha T172, a marker of AMPK activation, in both acute myeloid leukemia (AML) cell lines and primary AML samples. GSK621 is reported to reduce the proliferation of AML cell lines (IC50 s = 13-30 µM), triggering autophagy via the eIF2Alpha/ATF4 signaling pathway. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-chloro-5-(2'-hydroxy-3'-methoxy[1,1'-biphenyl]-4-yl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione |
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| Gene, Accession, CAS # | CAS: 1346607-05-3 |
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| Catalog # | LS-H8025 |
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| Price | |
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| Order / More Info | GSK621 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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