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| Product Name | CAY10416 |
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| Description | CAY10416 is a dual COX-2/5-LO inhibitor with IC50 values of 50 and 3 nM, respectively.{10003} The selectivity of CAY10416 for COX is greater than 200-fold for COX-2 versus COX-1. COX-2/5-LO inhibitors such as CAY10416 are also apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy. In the PC3 human carcinoma cell line, CAY10416 exhibits a 45% inhibition of proliferation at 100 µM. In the LNCaP human carcinoma cell line, CAY10416 inhibits growth with an IC50 value of 83 µM. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | COX-2 cyclooxygenases 5-LO lipoxygenases inflammation inhibitors prostates cancers PC3 LNCaP carcinomas apoptosis inhibition inhibits chemotherapy cells lines |
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| Gene, Accession, CAS # | CAS: 443919-96-8 |
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| Catalog # | 70635-1 |
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| Price | |
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| Order / More Info | CAY10416 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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