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Product Name | AMG-925 |
Description | AMG-925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively. It inhibits the proliferation of a panel of human tumor cell lines including Colo205 (Rb(+)) and U937 (FLT3(WT)) and induces cell death in MOLM13 (FLT3(ITD)). MW: 471.55. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-hydroxy-1-[2-[[9-(4-methylcyclohexyl)pyrido[4,5]pyrrolo[1,2-d]pyrimidin-2-yl]amino]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]ethenone |
Gene, Accession, CAS # | CAS: 1401033-86-0 |
Catalog # | B1959-5 |
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Order / More Info | AMG-925 from BIOVISION, INC. |
Product Specific References | n/a |
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