产品详情 |
Edit |   |
Product Name | Protein G Resin |
Description | Protein G, a bacterial cell wall protein isolated from group G Streptococci, binds to mammalian IgGs mainly through Fc regions. Native protein G has 3 IgG binding domains and also sites for albumin and cell-surface binding. The latter have been eliminated from recombinant protein G to reduce nonspecific binding. Although protein G has very similar tertiary structures to protein A, their amino acid compositions differ significantly, resulting in different binding characteristics. Protein G can be used for purification of mammalian monoclonal and polyclonal IgGs that do not bind well to protein A. Protein G has greater affinity than protein A for most mammalian IgGs, especially for certain subclasses including human IgG3, mouse IgG1 and rat IgG2a. Unlike protein A, protein G does not bind to human IgM, IgD and IgA. |
Size | 5 mL |
Concentration | n/a |
Applications | Affinity Chromatography (AC) |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN1536254 |
Price | |
Order / More Info | Protein G Resin from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 18083829, 20678659, 21307336, 21576699, 22357953, 22615402, 23083132, 23616553, 24191297, 24420080, 24445600, 24596086, 25002536, 25171010, 25173632, 25238963, 25610950, 25913091, 25914160 |
产品资料 |
|
|