产品名称 PION Antibody from CREATIVE DIAGNOSTICS
产品货号 CABT-BL2903
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE DIAGNOSTICS
产品概述
产品详情
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Antigenic SpecificityPION
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsIHC
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DescriptionRabbit Anti-Human PION polyclonal antibody for IHC. Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD; MIM 104300). Formation of;amyloid-beta is catalyzed by gamma-secretase (see PSEN1; MIM 104311), a protease with numerous substrates. PION, or;GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both;gamma-secretase and its substrate, the amyloid-beta precursor protein (APP; MIM 104760) C-terminal fragment (APP-CTF);(He et al., 2010 (PubMed 20811458)).
ImmunogenRecombinant Protein
Other Namesn/a
Gene, Accession #Gene ID: 54103, UniProt: A4D1B5
Catalog #CABT-BL2903
Price
Order / More InfoPION Antibody from CREATIVE DIAGNOSTICS
Product Specific Referencesn/a
产品资料