产品详情 |
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Antigenic Specificity | Human IGF2BP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Human IGF2BP3 polyclonal antibody for IHC-P. Insulin-like growth factor-II messenger RNA (mRNA) -binding protein-3 (IMP-3) , also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies. IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor. |
Immunogen | Synthetic peptide |
Other Names | n/a |
Gene, Accession # | Gene ID: 10643, UniProt: O00425 |
Catalog # | DCABH-6390 |
Price | |
Order / More Info | Human IGF2BP3 Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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