| 产品详情 |
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| Antigenic Specificity | TP63 |
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| Clone | 22G23.2 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | Alexa Fluor® 488 conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ICC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-Human TP63 monoclonal antibody for ICC. Tumor protein 63 (UniProt Q9H3D4; also known as Amplified in squamous cell carcinoma, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p73L, TP63, Transformation-related protein 63, Tumor protein p73-like) is encoded by the TP63 (also known as KET, P63, P73H, P73L, TP73L) gene (Gene ID 8626) in human. Tumor protein 63 is a p53 homologue that can bind p53-responsive elements to upregulate some p53 target genes and share partially overlapping functions with p53. Various functions have been ascribed to TP63 in normal squamous epithelia, including those of the esophagus and TP63 is reported to play an essential role in the maintenance of proliferative potential in epithelial stem cells. TP63 overexpression is found in various squamous epithelia carcinomas and high TP63 expression is associated with an aggressive phenotype and metastasis in many cancers. |
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| Immunogen | KLH-conjugated linear peptide corresponding to human P40 near the N-terminus. |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 8626, UniProt: Q9H3D4 |
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| Catalog # | CABT-B1160 |
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| Price | |
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| Order / More Info | TP63 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 产品资料 |
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