| 产品详情 |
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| Antigenic Specificity | Androgen Receptor (N-Term) |
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| Clone | SN365 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human Androgen Receptor (N-Term) monoclonal antibody for IHC,WB. The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
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| Immunogen | A peptide corresponding to the N-terminus of Androgen Receptor |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 367, UniProt: P10275 |
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| Catalog # | CABT-BL8503 |
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| Order / More Info | Androgen Receptor (N-Term) Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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