产品详情 |
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Antigenic Specificity | CD2AP (aa 450-550) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB, ICC/IF, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Human CD2AP polyclonal antibody for WB, ICC/IF, IHC-P. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008] |
Immunogen | Synthetic peptide |
Other Names | n/a |
Gene, Accession # | Gene ID: 23607, UniProt: Q9Y5K6 |
Catalog # | CABT-BL909 |
Price | |
Order / More Info | CD2AP (aa 450-550) Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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