| 产品详情 |
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| Product Name | AZD-7762 |
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| Description | MW: 362.42. Purity ≥98% by HPLC. Background: AZD7762 is a potent, ATP-competitive, reversible, checkpoint kinase inhibitor with IC??s at 5 nM and <10 nM for Chk1 and Chk2, respectively. AZD 7762 abrogates DNA damage-induced S and G2 checkpoints with an EC?? value of 10 nM and potentiates the efficacy of DNA-damage repair prohibitive agents, gemcitabine and topotecan, both in vitro and in various tumor xenografts by modulating downstream checkpoint pathway proteins. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [(S)-5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide] |
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| Gene, Accession, CAS # | CAS: 860352-01-8 |
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| Catalog # | MBS842348 |
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| Order / More Info | AZD-7762 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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