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| Product Name | Colistin sulfate (USP Grade) |
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| Description | Mixture by primarly colistin A and B.. Very potent polymyxin antibiotic. Has only one amino acid difference compared to polymyxin B. Antimicrobial. Targets the lipopolysaccharide (LPS) of the outer membrane of Gram-negative bacteria. Competitively displaces divalent cations (Ca2+ and Mg2+) from the negatively-charged phosphate groups LPS, causing disruption of the membrane. This increases the permeability of the cell envelope, leakage of cell contents, leading to apoptosis and cell death. Used against multidrug-resistant Gram-negative bacterial infections. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Polymyxin E, Belcomycin, Colimycin |
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| Gene, Accession, CAS # | CAS: 1264-72-8 |
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| Catalog # | LS-H175 |
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| Order / More Info | Colistin sulfate (USP Grade) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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