| Edit |   |
|---|
| Antigenic Specificity | GTF2I |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 100 µl, 200 µl |
|---|
| Concentration | > 1 mg/ml |
|---|
| Applications | WB, IHC, IF/ICC, FCM. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | GTF2I Antibody is a Rabbit Polyclonal antibody against GTF2I. The GTF2I gene encodes a transcription factor. It negatively regulates agonist-induced calcium entry into cells by interfering with expression of the cation channel TRPC3 at the plasma membrane [PMID: 17023658]. As a transcription factor and/or as a regulator of intracellular calcium levels, GTF2I may play a role in the molecular basis of anxiety[PMID: 22578324]. It interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation [PMID: 16738337]. |
|---|
| Immunogen | Recombinant protein of human GTF2I. |
|---|
| Other Names | BAP-135; BAP135; BTKAP1; DIWS; FLJ38776; FLJ56355; IB291; SPIN; TFII-I; WBS; WBSCR6; General transcription factor II-I; GTFII-I; Bruton tyrosine kinase-associated protein 135; BTK-associated protein 135; SRF-Phox1-interacting protein; Williams-Beuren syndrome chromosomal region 6 protein; GTF2I |
|---|
| Gene, Accession # | GTF2I, Gene ID: 2969, SwissProt: P78347 |
|---|
| Catalog # | abx000783 |
|---|
| Price | |
|---|
| Order / More Info | GTF2I Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|