| 产品详情 |
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| Product Name | KL-001 |
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| Description | Purity >98% by NMR, TLC. KL-001 is a novel tool that specifically interacts with cryptochrome (CRY) preventing its ubiquitin-dependent degradation resulting in lengthening of the circadian period. KL-001-mediated CRY stabilization inhibits glucagon-induced gluconeogenesis in primary hepatocytes. Binds to the FAD-binding pocket of CRY2 as determined by co-crystal structure. KL-001 induces an increase in period along with simultaneous reduction in amplitude of circadian reporter expression in mammalian cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)methanesulfonamide |
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| Gene, Accession, CAS # | CAS: 309928-48-1 |
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| Catalog # | LS-H14732 |
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| Price | |
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| Order / More Info | KL-001 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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