| 产品详情 |
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| Antigenic Specificity | Acetylcholinesterase/ACHE |
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| Clone | 684CT8.3.4 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | Protein G purified |
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| Size | 400 ul |
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| Concentration | 0.5 mg/ml |
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| Applications | Western Blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The Acetylcholinesterase/ACHE Antibody (684CT8.3.4) from Novus Biologicals is a mouse monoclonal antibody to Acetylcholinesterase/ACHE. This antibody reacts with human, mouse, rat. The Acetylcholinesterase/ACHE Antibody (684CT8.3.4) has been validated for the following applications: Western Blot. Acetylcholinesterase Antibody (684CT8.3.4) (C-term) - Protein Information Function: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. Subunit structure: Interacts with PRIMA1. The interaction with PRIMA1 is required to anchor it to the basal lamina of cells and organize into tetramers By similarity. Isoform H generates GPI-anchored dimers; disulfide linked. Isoform T generates multiple structures, ranging from monomers and dimers to collagen-tailed and hydrophobic-tailed forms, in which catalytic tetramers are associated with anchoring proteins that attach them to the basal lamina or to cell membranes. In the collagen-tailed forms, isoform T subunits are associated with a specific collagen, COLQ, which triggers the formation of isoform T tetramers, from monomers and dimers. Isoform R may be monomeric. Polymorphism: Acetylcholinesterase is responsible for the Yt blood group system [MIM:112100]. The molecular basis of the Yt(a)=Yt1/Yt(b)=Yt2 blood group antigens is a single variation in position 353; His-353 corresponds to Yt(a) and the rare variant with Asn-353 to Yt(b). |
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| Immunogen | This Acetylcholinesterase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 587-611 amino acids from the C-terminal region of human Acetylcholinesterase. |
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| Other Names | acetylcholinesterase, acetylcholinesterase (Yt blood group), AChE, apoptosis-related acetylcholinesterase, ARACHE, EC 3.1.1, EC 3.1.1.7, N-ACHE, YT, Yt blood group |
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| Gene, Accession # | ACHE, Gene ID: 43, Accession: P22303, Q29499, SwissProt: P22303 |
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| Catalog # | NBP2-32061 |
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| Price | |
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| Order / More Info | Acetylcholinesterase/ACHE Antibody from NOVUS BIOLOGICALS, LLC |
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| Product Specific References | n/a |
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