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Product Name | LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 1-365) protein (His tag) |
Description | LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.Alternative Names: LIM and cysteine-rich domains protein 1, LMCD1, Dyxin |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | LMCD1|AW455500|AW553074|dyxin |
Gene, Accession, CAS # | Gene ID: 29995 |
Catalog # | ABIN1692523 |
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Order / More Info | LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 1-365) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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