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| Antigenic Specificity | Alkaline Phosphatase, Liver/bone/kidney (ALPL) (aa 31-45), (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alkaline phosphatase(ALPL) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at highpH . Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific(found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. ALPL is the alkaline phosphatase of skin fibroblasts,the tissue-nonspecific type, and that it is active toward millimolar concentrations of the putative natural substrates phosphoethanolamine(PEA) and pyridoxal-5-prime-phosphate(PLP). ALPL gene exists in single copy in the haploid genome and is composed of 12 exons distributed over more than 50 kb.Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human Alkaline Phosphatase(31-45aa DQAQETLKYALELQK), different from the related mouse and rat sequences by three amino acids. |
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| Other Names | ALP|iap|alpl|AP-TNAP|APTNAP|HOPS|TNAP|TNSALP|Akp-2|Akp2|PHOA|TNS-AP |
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| Gene, Accession # | Gene ID: 249 |
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| Catalog # | ABIN1672907 |
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| Order / More Info | Alkaline Phosphatase, Liver/bone/kidney (ALPL) (aa 31-45), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 3174660, 2220817 |
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