产品详情 |
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Antigenic Specificity | CDC42EP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. This CDC42EP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the C-terminal region of human CDC42EP2. |
Immunogen | Human CDC42EP2. |
Other Names | BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1; CDC42EP2 |
Gene, Accession # | CDC42EP2, SwissProt: O14613 |
Catalog # | abx029309 |
Price | |
Order / More Info | CDC42EP2 Antibody from ABBEXA |
Product Specific References | n/a |
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