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| Product Name | Glia Maturation Factor, beta (GMFB) protein |
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| Description | Glia Maturation Factor-Beta (GMF-Beta) is a 17 kDa protein nerve gorwth factor identified as a growth and differentiation factor in the vertebrate brain.Glia Maturation Factor-Beta stimulates differentiation of normal neurons as well as glial cells. GMFB inhibits the proliferation of the N-18 neuroblastoma line and the C6 glioma line while promoting their phenotypic expression.GMF-beta inhances the phenotypic expression of glia and neurons thus inhibits the proliferation of their respective tumors when added to cell culture. Although astrocytes produce GMF-b and stores it inside the cells, they don't secrete the GMF-B into the cultured medium. Cell- surface GMFb acts on the target cells at close range when cells are in direct contact. GMF-Beta is produced by thymic epithelial cells and plays an important role in T cell development in favor of CD4+ T cells.GMF-Beta is a brain-specific protein which belongs to the actin-binding proteins (ADF) family. GMF-beta appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines Synonyms: Glia maturation factor beta, GMFB, GMF-B, GMF-beta, GMF |
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| Size | 2 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | fc25b01|zgc:56451|zgc:86831|wu:fa97c03|wu:fc25b01|GMFB|DKFZp459J101|gmfb|GMF|3110001H22Rik|3110001O16Rik|AI851627|C79176|D14Ertd630e |
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| Gene, Accession, CAS # | Gene ID: 2764 |
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| Catalog # | ABIN804782 |
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| Order / More Info | Glia Maturation Factor, beta (GMFB) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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