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| Product Name | Glia Maturation Factor, beta (GMFB) (AA 1-142) protein |
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| Description | Glia Maturation Factor beta (GMF-beta) is a 17 kDa brain specific protein that belongs to the ADF/cofilin superfamily. It is a neurotrophin that induces maturation of neurons and glial cells, and. Unlike other neurotrophins, GMF-beta lacks a leader sequence and can be phosphorylated by protein kinase A and protein kinase C suggesting its role in signal transduction. GMF-beta is a prominent mediator of inflammation in the central nervous system and can activate several inflammation-related genes such as tumor necrosis factor-beta and interleukin-1beta. Researchers have shown there are significantly higher levels of GMF-beta protein in all the effected regions of Alzheimer's disease (AD) brains suggesting an important role of GMF-beta in AD pathogenesisRecombinant human Glia Maturation Factor beta (rhGMF-beta) produced in E. coli is a single non-glycosylated polypeptide chain containing 142 amino acids. rhGMF-beta has a molecular mass of 16.7kDa analyzed by reducing SDS-PAGE. Synonyms: GMFB |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | fc25b01|zgc:56451|zgc:86831|wu:fa97c03|wu:fc25b01|GMFB|DKFZp459J101|gmfb|GMF|3110001H22Rik|3110001O16Rik|AI851627|C79176|D14Ertd630e |
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| Gene, Accession, CAS # | Gene ID: 2764 |
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| Catalog # | ABIN2017879 |
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| Order / More Info | Glia Maturation Factor, beta (GMFB) (AA 1-142) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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