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| Product Name | Prostaglandin D2 Synthase 21kDa (Brain) (PTGDS) (C-Term), (AA 23-190) protein |
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| Description | Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala23-Gln190) of Human PTGDS fused with a polyhistidine tag at the C-terminus. Prostaglandin-H2 D-Isomerase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. PTGDS binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. It possibly participates in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor, blood-testis barrier, the central nervous system and male reproductive system. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PGDS|PTGDS|zgc:153919|XlCpl1|cerebrin-28|cpl-1|l-pgds|lpgds|pds|pgd2|pgds|pgds2|21kDa|L-PGDS|PGD2|PGDS2|Ptgs3|PH2DISO|LPGDS|PDS |
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| Gene, Accession, CAS # | Gene ID: 5730 |
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| Catalog # | ABIN1691434 |
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| Order / More Info | Prostaglandin D2 Synthase 21kDa (Brain) (PTGDS) (C-Term), (AA 23-190) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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