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| Antigenic Specificity | Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat, mouse |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.Subcellular location: Cell membrane, Single-pass type I membrane proteinTissue specificity: Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients. Also known as: LIGO1, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat and immunoglobilin domain-containing protein 1, Leucine-rich repeat neuronal protein 6A, Leucine-rich repeat neuronal protein 1, LERN1, LRRN6A. |
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| Immunogen | A synthetic peptide fromc-terminal region of human Lingo1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many other species. |
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| Other Names | lern1|lrrn6a|unq201|DKFZp459P0736|LERN1|LRRN6A|UNQ201|4930471K13Rik|AV148400|LINGO-1|Lrrn6a |
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| Gene, Accession # | Gene ID: 84894,235402,315691 |
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| Catalog # | ABIN571911 |
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| Order / More Info | Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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