| 产品详情 |
| Edit |   |
|---|
| Product Name | MI-773 |
|---|
| Description | MW: 562.51. Purity ≥98% by HPLC. MI-773; also known as SAR405838; is a spiro-oxindole that acts as a highly potent and selective MDM2 inhibitor. MI-773 binds to MDM2 with a Ki value of 0.88 nM and blocks the MDM2-p53 interaction. It activates wild-type p53 in vitro and in xenograft tumor tissue of leukemia and solid tumors; leading to p53-dependent cell cycle arrest and/or apoptosis. |
|---|
| Size | 1 mg, 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [(2'S; 3R; 4'S; 5'R)-6-chloro-4'- (3-chloro-2-fluorophenyl)-N- ( (1r; 4R)-4-hydroxycyclohexyl)-2'-neopentyl-2-oxospiro[indoline-3; 3'-pyrrolidine]-5'-carboxamide] |
|---|
| Gene, Accession, CAS # | CAS: 1303607-60-4 |
|---|
| Catalog # | MBS845790 |
|---|
| Price | |
|---|
| Order / More Info | MI-773 from MYBIOSOURCE INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|