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| Product Name | MGMT, 1-207aa, Human, His tag, E Coli |
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| Description | MW: 23.8 kDa (227 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher). Purity >95% by SDS-PAGE. O-6-methylguanine-DNA methyltransferase (MGMT) is an enzyme that repairs O-6-methylguanine, a mutagenic DNA base damaged by endogenous and environmental alkylating agents and is involved in the cellular defense against the biological effects of O-6-methylguanine in DNA. MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 positi |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [O-6-methylguanine-DNA methyltransferase; MGMT; EC 2.1.1.63; O-6-methylguanine-DNA-alkyltransferase; O-6-methylguanine-DNA methyltransferase 6 O methylguanine DNA methyltransferase; Agat; AGT; AI267024; MGC107020; Methylated DNA protein cysteine methyltransferase; Methylguanine DNA methyltransferase; O 6 methylguanine DNA alkyltransferase.] |
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| Gene, Accession, CAS # | MGMT, Gene ID: 4255, Accession: NP_002403 |
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| Catalog # | MBS203260 |
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| Order / More Info | MGMT, 1-207aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Matsukura S., et al. (2001) Annals of Surgical Oncology, 8 (10):807--816; Esteller M.,et al. (2002) J Natl Cancer Inst. 2, 26-32.; |
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