| 产品详情 |
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| Product Name | MG-132 |
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| Description | MW: 475.6. Purity ≥98% by HPLC. Background: A cell-permeable, potent, and reversible proteasome inhibitor (Ki = 4 nM). Reduces degradation of ubiquitin-conjugated proteins in mammalian cells and permeable strains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1), which initiates apoptosis. Inhibits NF-kB activation (IC?? = 3 uM). Prevents gamma-secretase cleavage. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Z-Leu-Leu-Leu-CHO; Z-LLL-CHO] |
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| Gene, Accession, CAS # | CAS: 133407-82-6 |
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| Catalog # | MBS842669 |
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| Order / More Info | MG-132 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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