产品详情 |
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Antigenic Specificity | Lipocalin 2 (LCN2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 200 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Lipocalin-2, a member of the lipocalin family of proteins, was originally identified as a gelatinase-associated component of neutrophil secretory granules. Lipocalin-2 is involved in innate immunity, iron homeostasis, and apoptosis. Lipocalin-2 limits bacterial growth by binding to bacterial siderophores and sequestering iron. In mammalian cells, iron-loaded lipocalin-2 binds to its receptor, 24p3R, and is internalized, thereby releasing iron and increasing the intracellular iron concentration. Conversely, iron-free lipocalin-2 promotes apoptosis. Lipocalin-2 is also expressed in adipose tissue and promotes insulin resistance in cultured mouse adipocytes.Synonyms: LCN2, 24p3, MSFI, NGAL, Lipocalin-2 |
Immunogen | Recombinant protein of human LCN2 |
Other Names | LCN2|24p3|MSFI|NGAL|AW212229|Sip24 |
Gene, Accession # | Gene ID: 3934,16819,170496 |
Catalog # | ABIN1514292 |
Price | |
Order / More Info | Lipocalin 2 (LCN2) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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