| 产品详情 |
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| Antigenic Specificity | CAND1, N-terminus |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | delipidated & defibrinated |
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| Size | 100 µL |
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| Concentration | 85 mg/mL |
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| Applications | ELISA, Immunohistochemistry, Western Blot. This antibody reacts with human, rat and mouse CAND1 by western blot and immunoprecipita-tion. The antibody immunoprecipitates in vitro translated protein and protein from cell lysates (using HeLa and NIH-3T3, and others). Coimmunoprecipitation of related proteins has not been tested. A 136.4 kDa band corresponding to human CAND1 is detected. Most cell lines expressing CAND1 can be used as a positive control. Researchers should determine optimal titers for other applications. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human, rat and mouse CAND1/TIP120A. Cross reactivity does occur with human, rat and mouse CAND2/TIP120B. Cross reactivity with CAND1 from other sources is not known. |
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| Immunogen | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 11-24 of Human CAND1/TIP120A (N-terminal) coupled to KLH. |
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| Other Names | rabbit anti-CAND1 antibody, Cullin associated NEDD8 dissociated protein 1 antibody, p120 CAND1 antibody, TATA binding protein interacting protein, 20A antibody, TBP interacting protein antibody, TBP interacting protein of 120 kDa A antibody, TIP120 antibody |
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| Gene, Accession # | CAND1, Gene ID: 55832, NCBI: 21361794, UniProt: Q86VP6 |
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| Catalog # | 100-401-A11 |
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| Order / More Info | CAND1, N-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Feng S, Shen Y, Sullivan J, Rubio C, Xiong Y (2004) The Arabidopsis thaliana CAND1, an unmodified Cul1 interacting protein, is involved in multiple development pathways controlled by ubiquitin/proteasome-mediated protein degradation. Plant Cell. 2004 Jul; 16(7): 1870-1882. Cheng Y, Dai X, Zhao Y. (2004) AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis. Plant Physiol. 135(2):1020-6. Liu J, Furukawa M, Matsumoto T, Xiong Y.(2002) NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. Mol Cell. 10(6):1511-8. |
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