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| Product Name | DEDD, 1-318aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 38.9 kDa (338aa). Purity >85% by SDS-PAGE. Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpressi |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Death effector domain-containing protein; CASP8IP1; DEDD1; DEFT; FLDED1; KE05] |
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| Gene, Accession, CAS # | DEDD, Gene ID: 9191, Accession: NP_127491 |
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| Catalog # | MBS205493 |
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| Order / More Info | DEDD, 1-318aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Stegh A H., et al. (1998) EMBO J. 17:5974-5986.; Schickling O., et al. (2001) Cell Death Differ. 8:1157-1168. |
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