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| Product Name | Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 |
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| Description | 1-415aa; Full length of isoform 2. MW: 63.7kD. Purity >90% as determined by SDS-PAGE. The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-11] |
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| Gene, Accession, CAS # | PLCZ1, Gene ID: 89869, Accession: NP_149114.2 |
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| Catalog # | MBS1451131 |
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| Order / More Info | Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 from MYBIOSOURCE INC. |
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| Product Specific References | Sperm phospholipase Czeta from humans and cynomolgus monkeys triggers Ca2 oscillations, activation and development of mouse oocytes.Cox L.J., Larman M.G., Saunders C.M., Hashimoto K., Swann K., Lai F.A.Reproduction 124:611-623(2002) Rescue of defective pancreatic secretion in cystic-fibrosis cells by suppression of a novel isoform of phospholipase C.Zhu H., Zhu J.X., Lo P.S., Li J., Leung K.M., Rowlands D.K., Tsang L.L., Yu M.K., Jiang J.L., Lam S.Y., Chung Y.W., Zhou Z., Sha J., Chang Chan H.La |
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