| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 |
|---|
| Description | 1-762aa; Full Length. MW: 103.53kD. Purity >90% as determined by SDS-PAGE. Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca2+ from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca2+ mobilization in the zona pellu |
|---|
| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4 ] |
|---|
| Gene, Accession, CAS # | PLCD4, Gene ID: 84812, Accession: NP_116115.1 |
|---|
| Catalog # | MBS1367818 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 from MYBIOSOURCE INC. |
|---|
| Product Specific References | Phospholipase C delta-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells.Leung D.W., Tompkins C., Brewer J., Ball A., Coon M., Morris V., Waggoner D., Singer J.W.Mol. Cancer 3:15-15(2004) Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Assignment of the human PLC delta4 gene (PLCD4) to human chromosome band 2q35 by fluorescence in situ hybridization.Kim H., Suh P.-G., Ryu S.H., Park S.H.Cytogenet. Cell |
|---|
| 产品资料 |
|
|