| 产品详情 |
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| Antigenic Specificity | Protocadherin gamma (C-Term), (aa 808-931), (pan) |
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| Clone | S159-5 |
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| Host Species | Mouse |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | peroxidase (HRP) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. Cellular Localization: Cell Membrane |
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| Immunogen | Fusion protein corresponding to amino acids 808-931 (C-terminal cytoplasmic constant domain) of mouse Protocadherin-gamma-A1 that is shared by all 22 Gamma-protocadherins (A subfamily amino acids ~807-930, B subfamily amino acids ~789-912 and C subfamily amino acids ~818-941). 99% identity with human (123/124 amino acids). |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN1741192 |
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| Price | |
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| Order / More Info | Protocadherin gamma (C-Term), (aa 808-931), (pan) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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