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| Antigenic Specificity | T-Cell Leukemia/lymphoma 1A (TCL1A) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 200 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TCL1 (T cell leukemia 1), MTCP1 and TCL1b belong to the TCL1 proto-oncogene family, and their products are involved in Akt activation during embryonic development, T cell leukemias, prolymphocytic leukemias and B cell lymphomas. The Akt association domain of TCL1 binds with the PH domain of Akt. The formation of an oligomeric TCL-Akt complex is required for TCL1 coactivator function and results in phosphorylation and activation of Akt. Furthermore, functional analysis indicates that the interaction between TCL1 and Akt promotes translocation of Akt to the nucleus. These findings are supported by the crystal structure of TCL1, which suggests that TCL1 may participate in molecular transport.Synonyms: TCL1A, TCL1 |
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| Immunogen | Recombinant protein of human TCL1A |
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| Other Names | TCL1A|Tcl1a|TCL1|Tcl1 |
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| Gene, Accession # | Gene ID: 8115,21432,690575 |
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| Catalog # | ABIN1514736 |
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| Price | |
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| Order / More Info | T-Cell Leukemia/lymphoma 1A (TCL1A) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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