产品详情 |
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Antigenic Specificity | BRCA2 and CDKN1A Interacting Protein (BCCIP) |
Clone | 2067C4a |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein G purified |
Size | 50 µg |
Concentration | n/a |
Applications | Dot Blot (DB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. Synonyms: Monoclonal BCCIP antibody, Anti-BCCIP antibody, BRCA2 and CDKN1A-interacting protein antibody, TOK-1 antibody. |
Immunogen | BCCIP antibody was raised in mouse using recombinant Human Brca2 And Cdkn1 A Interacting Protein (Bccip) |
Other Names | zgc:110272|mp:zf637-1-000774|BCCIP|DKFZp459K2416|MGC82792|tok-1|MGC89311|TOK-1|TOK1|1110013J05Rik |
Gene, Accession # | Gene ID: 56647 |
Catalog # | ABIN932485 |
Price | |
Order / More Info | BRCA2 and CDKN1A Interacting Protein (BCCIP) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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