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| Product Name | Human CD89 Recombinant (FCAR) |
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| Description | MW: 32,265 Da. Purity >97%, as determined by SDS-PAGE and HPLC. FcRI/CD89 is a type I transmembrane glycoprotein expressed at the surface of myeloid cells and member of the Ig superfamily. CD89 binds both IgA1 and IgA2 with similar affinity. The site of interaction between CD89 and IgA was identified in the first extracellular domain of CD89 and the C2/C3 junction of IgA. CD89 is constitutively expressed as a 50- to 70-kDa protein on neutrophils and monocytes/macrophages, or as a 70- to 100-kDa |
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| Size | 0.02 mg, 0.1 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Human CD89 Recombinant (FCAR) ; FCAR; XXbac-BPG230H20; 5; CD89; cd-89] |
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| Gene, Accession, CAS # | CD89, Gene ID: 2204, Accession: NP_001991.1 |
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| Catalog # | MBS553142 |
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| Order / More Info | Human CD89 Recombinant (FCAR) from MYBIOSOURCE INC. |
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| Product Specific References | • a recombinant bispecific single-chain fragment variable specific for hla class ii and fcri (CD89) recruits polymorphonuclear neutrophils for efficient lysis of malignant b lymphoid cells .J. Immunol., Feb 2010; 184: 1210 - 1217. • inside-out regulation of fcri (CD89) depends on pp2a .J. Immunol., Sep 2008; 181: 4080 - 4088. • a bispecific antibody composed of a nonneutralizing antibody to the gp41 immunodominant region and an anti-CD89 antibody directs broad human immunodeficien |
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