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| Product Name | Human CD155 Recombinant |
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| Description | MW: 45,303 Da. Purity >95%, as determined by SDS-PAGE and HPLC. hPVR (CD155) is a member of the immunoglobulin (Ig) superfamily, with three linked extracellular Ig-like domains followed by a membrane-spanning domain and a cytoplasmic domain. Although a physiological function for CD155 is unknown, the protein binds specifically to the extracellular matrix component vitronectin (Lange et al., 2001). Transcriptional regulation of the CD155 gene is tightly controlled. |
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| Size | 0.02 mg, 0.1 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [cd-155; PVR; CD155; HVED; NECL5; Necl-5; PVS; TAGE4] |
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| Gene, Accession, CAS # | CD155, Gene ID: 5817, Accession: NP_001129240.1 |
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| Catalog # | MBS553217 |
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| Order / More Info | Human CD155 Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • dnam-1/CD155 interactions promote cytokine and nk cell-mediated suppression of poorly immunogenic melanoma metastases .J. Immunol., Jan 2010; 184: 902 - 911. • primary human tumor cells expressing CD155 impair tumor targeting by down-regulating dnam-1 on nk cells .J. Immunol., Oct 2009; 183: 4921 - 4930. • cd96 interaction with CD155 via its first ig-like domain is modulated by alternative splicing or mutations in distal ig-like domains .J. Biol. Chem., Jan 2009; 284: 2235 - 224 |
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